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Maintenance and Cleaning

Maintenance

Users should not attempt to service or repair the Thermocycler themselves. If you have concerns about the module's performance or require maintenance, please contact Opentrons Support.

Cleaning

The following table lists the chemicals you can use to clean your Thermocycler. Diluted alcohol and distilled water are our recommended cleaning products, but you can refer to this list for other cleaning options.

Warning

  • Do not use acetone to clean the Thermocycler.
  • Do not disassemble the Thermocycler for cleaning or attempt to clean its internal electronic components or mechanical parts.
  • Do not put the Thermocycler in an autoclave.
Solution Recommendations
Alcohol Includes ethyl/ethanol, isopropyl alcohol, and methanol.
Dilute to 70% for cleaning.
Do not use 100% alcohol.
Bleach Dilute to 10% (1:10 bleach/water ratio) for cleaning.
Do not use 100% bleach.
Distilled Water You can use distilled water to clean or rinse your Thermocycler.

Be sure to turn the Thermocycler's power off before cleaning it. You can clean the top surfaces of the module while it is installed in a deck slot. However, for better access, you may want to:

  • Disconnect any USB or power cables before you begin.
  • Remove the caddy (Flex only) and module from the deck slot.
  • Remove the module from the caddy (Flex only).

Once you’ve prepared the module for cleaning:

  1. Dampen a soft, clean cloth or paper towel with a cleaning solution.
  2. Gently wipe off the module's surfaces.
  3. Rinse off any remaining residue using a cloth dampened with distilled water.
  4. Let the module air dry.

For information about cleaning the rubber seal, see the seal attachment instructions.